ProductDescription
Methoxypoly(ethyleneglycol)-Iodolacetyl(MPEG-IA)isonetypeoflinearmonofunctionalPEGacidreagents.聽PEG-IAcanbeusedtoreactwiththiol聽groups.
Haloacetylreactionchemistry:Themostcommonlyusedhaloacetylcrosslinkerscontainaniodoacetylorabromoacetylgroup.HaloacetylsreactwithsulfhydrylgroupsatphysiologicpH.Thereactionoftheiodoacetylgroupproceedsbynucleophilicsubstitutionofiodinewithasulfuratomfromasulfhydrylgroup,resultinginastablethioetherlinkage.