ProductDescription
CyclosporineA,聽alsospelled聽cyclosporine聽and聽cyclosporin,聽聽isanaturalcyclicpolypeptideimmunosuppressantisolatedfromthefungusBeauverianivea.Theexactmechanismofactionofcyclosporineisnotknownbutmayinvolvebindingtothecellularproteincytophilin,resultingininhibitionoftheenzymecalcineurin.ThisagentappearstospecificallyandreversIBLyinhibitimmunocompetentlymphocytesintheG0-orG1-phaseofthecellcycle.T-lymphocytesarepreferentiallyinhibitedwithT-helpercellsastheprimarytarget.Cyclosporinealsoinhibitslymphokineproductionandrelease.
Name:CyclosporineA
CAS#:59865-13-3
ChemicalFormula:C62H111N11O12
ExactMass:1201.84137
MolecularWeight:1202.61124
ElementalAnalysis:C,61.92;H,9.30;N,12.81;O,15.96
CyclosporinA,聽98%(HPLC)