ProductDescription
Cisplatinisapotentinducerofgrowtharrestand/orapoptosisinmostcelltypes.
Cisplatinisaninorganicplatinumagent(cis-diamminedichloroplatinum)withantineoplasticactivity.Cisplatinformshighlyreactive,charged,platinumcomplexeswhichbindtonucleophilicgroupssuchasGC-richsitesinDNA,inducingintrastrandandinterstrandDNAcross-links,aswellasDNA-proteincross-links.Thesecross-linksresultinapoptosisandcellgrowthinhibition.