ProductDescription
AbarelixisasyntheticdecapeptideandantagoNISTofnaturallyoccurringgonadotropin-releasinghormone(GnRH).Abarelixdirectlyandcompetitivelybindstoandblocksthegonadotropinreleasinghormonereceptorintheanteriorpituitarygland,therebyinhibitingthesecretionandreleaseofluteinizinghormone(LH)andfolliclestimulatinghormone(FSH).Inmales,theinhibitionofLHsecretionpreventsthereleaseoftestosterone.Asaresult,thismayrelievesymptomsassociatedwithprostatehypertrophyorprostatecancer,sincetestosteroneisrequiredtosustainprostategrowth.